Compounded Medication Formulary

Semaglutide

GLP-1 receptor agonist that reduces appetite and improves glycemic control. Titrated weekly dosing allows gradual adaptation with minimal GI side effects.

For patients with BMI ≥30 (or ≥27 with comorbidities) seeking medically supervised weight loss.

Key benefits: Significant weight reduction (12–17% body weight), improved A1c, cardiovascular risk reduction, reduced visceral adiposity.

⚠ Available for compounding subject to FDA drug shortage list status. Availability may change. Contact us for current status.

Tirzepatide

Dual GIP/GLP-1 receptor agonist offering enhanced efficacy through complementary incretin pathways. Superior weight loss outcomes compared to single-agonist therapy.

For patients seeking maximum weight loss efficacy, especially those with concurrent insulin resistance or type 2 diabetes.

Key benefits: Up to 20–25% body weight reduction in trials, superior glycemic control, improved lipid profiles, potential cardiovascular benefits.

⚠ Available for compounding subject to FDA drug shortage list status. Availability may change. Contact us for current status.

BPC-157 (Body Protection Compound)

Pentadecapeptide derived from gastric juice with potent tissue-healing and cytoprotective properties. Promotes angiogenesis, modulates nitric oxide, and accelerates tendon/ligament repair.

For patients with musculoskeletal injuries, GI issues (leaky gut, IBS), post-surgical recovery, or tendinopathy.

Key benefits: Accelerated wound/tendon healing, gut mucosal repair, anti-inflammatory effects, neuroprotective properties.

ℹ Currently under FDA review for compounding reclassification. Expected return to Category 1 status. Contact us for current formulary availability.

Sermorelin

Growth hormone-releasing hormone (GHRH) analog that stimulates physiologic GH secretion from the anterior pituitary. Maintains natural pulsatile GH release patterns and feedback mechanisms.

For patients with age-related GH decline, poor sleep quality, reduced lean mass, or slow recovery from exercise.

Key benefits: Improved sleep architecture, increased lean body mass, enhanced recovery, better skin elasticity, reduced visceral fat.

CJC-1295 / Ipamorelin

Synergistic GHRH analog + ghrelin mimetic combination. CJC-1295 extends GH-releasing pulses while Ipamorelin provides selective GH secretagogue activity without cortisol or prolactin elevation.

For patients seeking optimized GH axis support, anti-aging benefits, improved body composition, and enhanced recovery.

Key benefits: Amplified GH release, improved sleep, increased lean mass, fat loss, enhanced collagen synthesis, faster recovery.

ℹ Currently under FDA review for compounding reclassification. Expected return to Category 1 status. Contact us for current formulary availability.

GHK-Cu (Copper Peptide)

Naturally occurring tripeptide-copper complex that declines with age. Potent activator of tissue remodeling, collagen synthesis, and stem cell recruitment.

For patients seeking skin rejuvenation, wound healing, hair regrowth support, or anti-aging tissue repair.

Key benefits: Stimulates collagen/elastin synthesis, promotes wound healing, hair follicle support, anti-inflammatory, antioxidant.

ℹ Topical formulations currently available. Injectable form under FDA review for compounding reclassification.

Thymosin Alpha-1

Endogenous thymic peptide with broad immunomodulatory effects. Enhances dendritic cell maturation, T-cell function, and NK cell activity. FDA-orphan drug designation for hepatitis B.

For patients with immune dysregulation, chronic viral infections, autoimmune conditions, or seeking immune system optimization.

Key benefits: Enhanced innate and adaptive immunity, improved vaccine response, antiviral activity, immune rebalancing.

PT-141 / Bremelanotide

Melanocortin receptor agonist (MC3R/MC4R) that acts centrally on the hypothalamus to enhance sexual arousal and desire. Works via a distinct mechanism from PDE5 inhibitors.

For patients with hypoactive sexual desire disorder (HSDD), erectile dysfunction, or diminished libido unresponsive to hormonal therapy alone.

Key benefits: Increased sexual desire and arousal, effective in both men and women, works through central nervous system pathways.

AOD-9604

Modified fragment of human growth hormone (hGH176-191) that retains fat-metabolizing activity without GH’s proliferative or diabetogenic effects. Stimulates lipolysis and inhibits lipogenesis.

For patients seeking targeted fat reduction without the metabolic side effects of exogenous GH therapy.

Key benefits: Enhanced fat metabolism, no impact on blood glucose or IGF-1, cartilage regeneration properties, favorable safety profile.

ℹ Currently under FDA review for compounding reclassification. Expected return to Category 1 status.

MOTS-c

Mitochondrial-derived peptide that activates AMPK signaling, improving cellular energy metabolism. Enhances insulin sensitivity and exercise capacity at the molecular level.

For patients seeking metabolic optimization, improved exercise performance, and cellular energy enhancement.

Key benefits: Improved insulin sensitivity, enhanced fat oxidation, increased exercise endurance, mitochondrial biogenesis support.

ℹ Currently under FDA review for compounding reclassification.

Epithalon (Epitalon)

Synthetic tetrapeptide (Ala-Glu-Asp-Gly) that activates telomerase, promoting telomere elongation. Based on research by Prof. Khavinson demonstrating lifespan extension in animal models.

For patients pursuing advanced longevity strategies, telomere maintenance, and biological age optimization.

Key benefits: Telomerase activation, potential cellular rejuvenation, improved circadian rhythm regulation, antioxidant properties.

⚠ Availability subject to current FDA compounding regulations. Contact us for current formulary status.

Selank

Synthetic heptapeptide analog of tuftsin with anxiolytic and nootropic properties. Modulates GABA, serotonin, and dopamine systems without sedation or dependence potential.

For patients with anxiety, cognitive decline, or seeking non-benzodiazepine anxiolytic support with cognitive enhancement.

Key benefits: Anxiolytic without sedation, enhanced memory and learning, immune modulation, BDNF upregulation.

ℹ Currently under FDA review for compounding reclassification.

Semax

Synthetic peptide derived from ACTH(4-10) with potent neurotrophic and neuroprotective effects. Increases BDNF expression and modulates serotonergic and dopaminergic systems.

For patients seeking cognitive enhancement, neuroprotection, improved focus, or recovery from neurological events.

Key benefits: Enhanced focus and memory, BDNF/NGF upregulation, neuroprotection, improved cerebral circulation.

ℹ Currently under FDA review for compounding reclassification.

KPV

Tripeptide fragment of alpha-MSH (Lys-Pro-Val) with potent anti-inflammatory properties. Inhibits NF-κB signaling and reduces inflammatory cytokine production.

For patients with inflammatory bowel conditions, systemic inflammation, or chronic inflammatory states.

Key benefits: Potent NF-κB inhibition, gut mucosal healing, systemic anti-inflammatory, antimicrobial activity.

ℹ Currently under FDA review for compounding reclassification.

LL-37

Human cathelicidin antimicrobial peptide with broad-spectrum activity against bacteria, viruses, and fungi. Also modulates immune responses and promotes wound healing.

For patients with chronic infections, biofilm-related illness, or requiring innate immune system support.

Key benefits: Broad antimicrobial activity, biofilm disruption, immune modulation, wound healing promotion.

⚠ Availability subject to current FDA compounding regulations.

Dihexa

Hexapeptide analog of angiotensin IV with extraordinary neurotrophic potency. Promotes synaptogenesis and neuronal connectivity via HGF/MET receptor activation.

For patients with cognitive decline, traumatic brain injury recovery, or seeking advanced neurocognitive support.

Key benefits: Potent synaptogenesis, enhanced memory consolidation, HGF/MET receptor activation, improved neuroplasticity.

⚠ Availability subject to current FDA compounding regulations.

TB-500 / Thymosin Beta-4

43-amino acid peptide involved in tissue repair, cell migration, and angiogenesis. Upregulates actin to promote cellular migration to injury sites and modulates inflammatory responses.

For patients with musculoskeletal injuries, chronic wounds, cardiac tissue repair, or post-surgical recovery.

Key benefits: Accelerated tissue repair, reduced inflammation, improved flexibility, angiogenesis promotion, cardiac protection.

ℹ Currently under FDA review for compounding reclassification. Expected return to Category 1 status.

Testosterone

Bioidentical testosterone for replacement in hypogonadal men and adjunctive therapy in women. Custom-compounded to precise dosing not available commercially.

For men with confirmed low testosterone (Total T <300 ng/dL or symptomatic <400). Women with low libido, fatigue, or sarcopenia.

Key benefits: Restored energy and libido, improved lean mass and bone density, enhanced cognition and mood, cardiovascular benefits.

Estradiol

Bioidentical 17β-estradiol for menopausal hormone therapy. Compounded in customized doses and delivery forms to match individual patient needs.

For perimenopausal and postmenopausal women with vasomotor symptoms, vaginal atrophy, bone loss, or symptomatic estrogen deficiency.

Key benefits: Relief of hot flashes, improved vaginal health, bone density preservation, cardiovascular protection, mood stabilization.

Progesterone

Bioidentical micronized progesterone for HRT and sleep support. Essential companion to estradiol therapy for endometrial protection with additional neurosteroid benefits.

For women on estradiol replacement, perimenopausal women with insomnia, or those with progesterone deficiency symptoms.

Key benefits: Endometrial protection, improved sleep via GABA modulation, anxiolytic effects, neuroprotection.

DHEA

Adrenal precursor hormone that serves as a substrate for androgen and estrogen biosynthesis. Levels decline approximately 80% from peak by age 70.

For patients with documented low DHEA-S levels, adrenal insufficiency, or age-related hormonal decline.

Key benefits: Improved energy and well-being, immune support, bone density, enhanced libido, neuroprotection.

Pregnenolone

Master neurosteroid precursor at the top of the steroidogenic cascade. Converts to DHEA, progesterone, cortisol, and downstream sex hormones as needed.

For patients with cognitive decline, low neurosteroid levels, or as part of comprehensive hormone optimization.

Key benefits: Cognitive enhancement, memory support, mood regulation, upstream hormonal support, neuroprotection.

Thyroid T3/T4 (Compounded)

Custom-compounded thyroid hormones in precise T3:T4 ratios not available commercially. Sustained-release T3 formulations provide stable serum levels.

For patients with suboptimal thyroid function, poor T4→T3 conversion, or those requiring customized T3:T4 ratios.

Key benefits: Optimized energy and metabolism, improved cognitive function, stable T3 levels, customizable dosing.

Oxytocin

Neuropeptide with roles in social bonding, mood regulation, sexual function, and stress response. Compounded in sublingual and intranasal forms.

For patients with mood disorders, social anxiety, sexual dysfunction, or seeking enhanced emotional well-being.

Key benefits: Improved mood and social connection, enhanced sexual function, anxiolytic effects, stress resilience.

NAD+ (Nicotinamide Adenine Dinucleotide)

Essential coenzyme in cellular energy metabolism that declines ~50% by age 50. Direct NAD+ supplementation bypasses rate-limiting steps in oral precursor pathways (NR/NMN).

For patients seeking cellular rejuvenation, improved energy, neuroprotection, and sirtuin/PARP enzyme optimization.

Key benefits: Enhanced cellular energy, DNA repair support, sirtuin activation, neuroprotection, improved metabolic function.

Metformin

Biguanide with AMPK-activating and mTOR-inhibiting properties beyond glucose control. TAME trial investigating anti-aging effects. Custom-compounded ER formulations for improved GI tolerance.

For patients pursuing longevity optimization, metabolic syndrome management, or AMPK activation strategies.

Key benefits: AMPK activation, reduced cancer risk (epidemiologic data), improved insulin sensitivity, anti-inflammatory, potential lifespan extension.

Rapamycin (Sirolimus)

mTOR inhibitor with the most robust lifespan extension data in mammalian models. Low-dose pulsed protocols leverage mTORC1 inhibition while sparing mTORC2-mediated immune function.

For patients pursuing advanced longevity strategies under physician supervision. Requires baseline labs and ongoing monitoring.

Key benefits: mTORC1 inhibition, enhanced autophagy, senolytic-adjacent effects, improved immune function (low-dose), potential healthspan extension.

Tadalafil / Sildenafil (Compounded)

PDE5 inhibitors compounded in custom doses and combination formulations not commercially available. Sublingual troches offer faster onset; low-dose daily tadalafil provides continuous coverage.

For men with erectile dysfunction. Custom combination formulations available for multi-mechanism approach.

Key benefits: Improved erectile function, custom dosing flexibility, combination formulations, endothelial health benefits (tadalafil).

PT-141 / Bremelanotide (Sexual Health)

Central-acting melanocortin agonist for desire-based sexual dysfunction. Unlike PDE5 inhibitors, PT-141 addresses libido and arousal at the neurological level.

For men and women with low desire/arousal disorders, or as adjunct to PDE5 inhibitors when arousal alone is insufficient.

Key benefits: Increased sexual desire, works in both sexes, central mechanism of action, complements hormonal and vascular therapies.

Oxytocin (Sexual Health)

Enhances arousal, orgasm intensity, and emotional bonding. Used as PRN adjunct to improve sexual experience and satisfaction in both men and women.

For patients seeking enhanced sexual pleasure, improved orgasm quality, and deeper emotional connection.

Key benefits: Enhanced arousal and orgasm, emotional bonding, stress reduction, complements other sexual health therapies.

Dutasteride / Minoxidil Compound

Combination topical with dual 5-alpha reductase inhibition (dutasteride) and vasodilator-mediated follicle stimulation (minoxidil). Topical delivery minimizes systemic side effects.

For men and women with androgenetic alopecia, thinning hair, or those seeking to avoid systemic 5-AR inhibitors.

Key benefits: Dual-mechanism hair regrowth, minimized systemic absorption, convenient single-application formulation.

GHK-Cu Topical (Hair)

Copper peptide that stimulates hair follicle growth, increases follicle size, and promotes the anagen (growth) phase. Supports scalp vascularity and follicular stem cell activation.

For patients with thinning hair, receding hairline, or as adjunctive therapy to dutasteride/minoxidil compounds.

Key benefits: Follicle enlargement, extended anagen phase, improved scalp health, synergistic with other hair loss therapies.

Tretinoin (Compounded)

Gold-standard retinoid for photoaging, compounded in custom concentrations and vehicle formulations. Can be combined with other actives (niacinamide, hyaluronic acid).

For patients with photoaging, fine lines, hyperpigmentation, acne, or seeking medical-grade skin rejuvenation.

Key benefits: Increased collagen synthesis, accelerated cell turnover, improved skin texture and tone, reduced hyperpigmentation.

GHK-Cu Topical (Skin)

Copper peptide complex that stimulates collagen, elastin, and glycosaminoglycan synthesis. Promotes skin remodeling and reduces fine lines through growth factor signaling.

For patients seeking anti-aging skin therapy, wound healing support, or post-procedure skin recovery.

Key benefits: Collagen/elastin stimulation, wound healing, antioxidant protection, improved skin firmness and elasticity.